بررسی اثرضدباکتریایی پوسته توتیای دریایی گونه Echinometra mathaei ساحل چابهار

نوع مقاله: مقاله پژوهشی

نویسندگان

1 استادیار گروه زیست شناسی دریا، دانشکده علوم دریایی دانشگاه دریانوردی و علوم دریایی چابهار

2 دانشجوی کارشناسی ارشد زیست شناسی دریا، دانشکده علوم دریایی دانشگاه دریانوردی و علوم دریایی چابهار

چکیده

چکیده

خارپوستان گروهی قدیمی از بی‎مهرگان دریایی بوده که منبع غنی ترکیبات ضد­باکتری با مکانیسم فعالیت بالا هستند. هدف از مطالعه حاضر، بررسی اثر ضدباکتریایی پوسته توتیای دریایی گونه Echinometra mathaei در دوزهای مختلف، روی چند سویه­ باکتری بیماری‎زای انسانی است. پس از انجام نمونه­برداری و انتقال نمونه‎ها به آزمایشگاه، جانور تشریح و پوسته آن جدا و پس از شستشو و آسیاب شدن، توسط حلال کلروفرم عصاره­گیری صورت گرفت و غلظت­های مختلف 25/11-25/1 میلی‎گرم بر میلی‎لیتر تهیه شد و جهت تعیین فعالیت ضدباکتریایی آن­ها، روی باکتری‎های Staphylococcus aureus، Enterococcus faecalis، Escherichia coli و Klebsiella pneumonia از تست انتشار از دیسک استفاده شد. نتایج نشان داد که غلظت­های مختلف عصاره تهیه شده در باکتری‎های مختلف دارای اختلاف معنی‎داری هستند) 05/0(p

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