نوع مقاله : مقاله پژوهشی
نویسندگان
1 گروه زیست‌شناسی، دانشکده علوم پایه، دانشگاه شیراز، شیراز، ایران
2 گروه زیست‌شناسی، دانشگاه پیام نور، تهران، ایران
10.30473/eab.2025.75303.2002
چکیده
منابع طبیعی مانند گیاهان، یک گزینه درمانی مطمئن در درمان سرطان‌ها و کاهش عوارض جانبی روش‌های درمانی فعلی هستند. مریم‌گلی یک گیاه معطر و دارویی است که به‌دلیل خواص آنتی‌اکسیدانی خود شناخته شده است. این گیاه به‌عنوان یک عامل ضد اسپاسم، قابض، آرام‌بخش، ضد قند خون و ضد التهاب در طب ایرانی مورداستفاده قرار گرفته است. در پژوهش حاضر مطالعه اثرات ضد سرطانی ترکیبات موجود در عصاره‌های مریم‌گلی، مانند سینئول و کافور انجام گرفت. بدین منظور ابتدا در موش‌ها، سرطان توسط دی‌متیل‌بنز آنتراسن (دی‌متیل‌بنزانتراسن) حل شده در روغن کنجد به‌مدت چهار هفته القا شد. سپس رده‌های سلولی توموری مختلف در معرض عصاره مریم‌گلی قرار گرفتند. بدین منظور گروه مورد آزمایش به‌مدت چهار هفته با عصاره هیدروالکلی برگ مریم‌گلی درمان شدند. درحالی‌که گروه کنترل آب مقطر دریافت کردند. سپس مقاطع بافتی از نمونه‌ها گرفته شده و گروه‌ها با یکدیگر از نظر آماری مقایسه گردیدند. یافته‌ها نشان‌دهنده اثرات درمانی مریم‌گلی بر سرطان القاشده می‌باشد. مریم‌گلی می‌تواند به‌طور بالقوه از سرطان پستان جلوگیری کند.
کلیدواژه‌ها
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