Experimental animal Biology

In collaboration with Payame Noor University and Iranian Society of Physiology and Pharmacology

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Editorial Board

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

Journal Metrics

News

Study on liver histopathological changes of Gold fish (Carassius auratus) during exposure to lethal and sub lethal concentrations of cadmium

Document Type : Article

Authors

1 Master Degree, Young Reasearchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran

2 Faculty, Department of Fisheries, Gorgan University of Agricultural and Natural Resources, Gorgan, Iran

3 Master Degree, Department of Fisheries, Faculty of Fisheries, Department of Natural Resources, University of Guilan, Some'esara

4 Master Degree, Department of Fisheries, Faculty of Environment Karaj, Iran

5 Master Degree, Department of Fisheries, Gorgan University of Agricultural and Natural Resources, Gorgan, Iran

Abstract

Abstract
The aim of current study was to evaluate the effects of heavy metal cadmium on liver tissue of gold fish during experimental condition. Study was in a week on 5 treatments and 3 replicates, five concentration (2.8, 5.6, 8.4 and 11.2 ppm respectively) of cadmium as 0 (control), 25%, 50%, 75% and 100% of LC50 were selected and tested. Histopathological changes were done using classic histology method in hematoxylin and eosin staining and using a light microscope and camera images properly installed and connected the camera to the computer system software was developed. The overall result of this study showed that in liver tissue exposed to cadmium over a week with increasing duration of exposure to pesticide exposure, a high level of toxin in the lesion by the most frequent lesions end of a week, was observed including necrosis, atrophy and cloudy swelling of the cell. Result of this study show that liver tissue have many lesions in response to cadmium in one week and it will be increase with concentration and duration of toxin, as it was seen highest amount of lesions at the end of experiment within last dose.
 

Keywords

References
Ariaii, M.; Hamidian, A.; Eagdari, S.; Poorbagher, H.; Ashrafi, S.; (2014). Histopathological changes liver Zebra fish (Aphanius sophiae) the effect of arsenic and cadmium. Journal of Aquatic Ecology; 3(4): 31-40.
Correia, P.M.R.; Oliveirra, E.; (2000). Simultaneouse ditermination of Cd and Pb in food stuff by lectrotermal atomic absorbtion spectrometry, a Analitical chimica acta; 405(1): 205-211.
Dural, M.; Ziya Lugal Goksu, M.; Ozak, A.A.; (2007). Investigation  of  heavy  metal  levels  in economically   mportant  fish  species  captured from  the  Tuzla  Lagoon.  Food Chem; 102(1): 415-421. 
Gochfeld; M.; (2003). Cases of mercury exposure bioavailability and absorption. Ecotoxicology and Environmental Safety; 56(1): 174-179.
Hansen, J.A.; Welsh, P.G.; Lipton, J.; Cacela, D.; Dailey, A.D.; (2002). Relative sensitivity of bull trout (Salvelinus confluentus) and rainbow trout (Oncorhynchus mykiss) to acute exposures of cadmium and zinc. Environmental toxicology and chemistry; 21(1), 67-75.
Hedayati, A.; Jahanbakhshi. A.; Ghaderiremazi, F.; (2013). Aquatic toxicology. Publications University of Agricultural Sciences and Natural Resources, Gorgan, Page 210. (In Persian).
Jaffar, M.; Ashraf, M.; Rasoal, A.; (1998). Heavy metal contents in some selected local freshwaters fish and relevant waters. Pakistan Journal of scientific and industrial research; 31(3): 189-193.
Karadede, H.; Unlu, E.; (2000). Concentrations of some heavy metals in water, sediment and fish species from the Ataturk dam lake (Euphrates). Turkey Chemosphere; 41: 1371-1376.
Langston, W.J.; (1990). Toxic effects of metals and the incidence of metal pollution in marine ecosystems. In R.W. Furness and P.S. Rainbow (editors), Heavy metals in the marine environment. Boca Raton, FL: CRC Press.
Mance, G.; (1990). Pollution at of Heavy Metals in Aquatic Enviroments. London: Elsevier applied science. UK. 372p.
Mansuri, B.; Poor Mohammad, A.; Babaii, H.; (2010). Determination of heavy metals in different tissues of black fish (Capoeta fusca) in the central part of the aqueduct of Birjand. Health and Reconstruction, 24(4): 45-52.
Massaro Edvard, J.; (1997). Handbook of toxicology National health and environment effects research  aboratory. CRC press Bocaraton New York, pp. 38-54.
Mercury, Lead, Cadmium, Tin and Arsenic in Food. Food safety.  (Accessed in Apr 10, 2013, at www.fsai.ie/WorkArea/Download Asset).
Mohammad nabizadeh, S.; Pour Khabaz, A.R.; (2013). To investigate the accumulation of Heavy metals cadmium and nickel in the tissues of fish (Platycephalus indicus) in mangrove wetlands.  Journal of Environmental Science and Engineering; 1(1): 39-44.  
Plasket, D.; Potter, I.; (1979). Heavy metal concenterations in the muscle tissue of 12 species of teleosts from cockborn sound, Western Australia. Australia Journal of Marin and Freshwater Research; 30(5): 607.
Pousti, A.; Sedigh Marvesti, A.; (1999). Atls fish histology, Tehran University Press. 328 pages.
Ricard, A.C.; Daniel, C.; Anderson, P.; Hontela, A.; (1998). Effects of subchronic exposure to cadmium chloride on endocrine and metabolic functions in rainbow trout (Oncorhynchus mykiss). Archives of environmental contamination and toxicology; 34(4), 377-381.
Roberts, R.J.; (2001). Fish Pathology, 3rd Edition. W.B. Saunders, Philadelphia, pp: 208-209, 372-375.
Rohn, M.; Tehagen, B.A.; Hafmann, W.; (2004). Survival of dairy cow after surgery to correct abomasal displacement. Veterinary Medicine series A; 51(6): 294-299.
Romeo, M.; Siau, Y.; Sidoumou, Z.; Gnassia-Barelli, M.; (1999). Heavy metal distribution in different fish species from the Mauritania coast. Science of the Total Environment; 232(3): 169-175.
Rostami­ bashman, M.; Soltani, M.; Sasani, F.; (2000). Study of the effects histopathological of heavy metals (Copper sulfate, zinc sulfate and mercury-cadmium chloride) the tissues of common carp. Journal of Veterinary Research (Tehran University); 55(4):1-3.
Sattari, M.; (2002). Systematic Ichthyology, Haghshenas publication. Tehran, Iran. (In Persian).
Schmalz, W.F.; Hernandez, A.D.; Weis, P.; (2002). Hepatic histopathology in two populations of the mummichog, Fundulus heteroclitus. Mar Environ. Res; 54(3-5): 539-542.
Shariat feizabadi, F.; (1998). Water Quality Standards. (In Persian).
Experimental animal Biology
Volume 3, Issue 4 - Serial Number 4
July 2015
Pages 9-16
Files
Share
How to cite
Statistics