In collaboration with Payame Noor University and Iranian Society of Physiology and Pharmacology

Document Type : Article

Authors

1 M.Sc. Student, Clinical Microbiology, Faculty of Medicine, Gorgan University of Medical Sciences

2 Associate Professor, Department of Microbiology, School of Medicine, Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

3 Ph.D. in Clinical Pharmacy, Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

4 Associate Professor, Medicinal Plant Research Center, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Abstract

Abstract
Bacterial resistance to antibiotics is main challenge in the treatment of infectious diseases. Thus, investigation for alternative drugs is an essential phenomenon. This study designed to aim to evaluate the antimicrobial property of essential oil of Boswellia carterii against bacterial and fungal causative agents of the mouth, gastrointestinal tract infections and antibiotic-resistant species. Essential oils were isolated through microdilution tube using Clevenger's method. The antimicrobial activities of the essential oils were individually evaluated against different microorganisms including pathogenic fungus (candida albican and three type of aspergillus), Gram-positive (Streptococcus salivarius, Streptococcus sanguis and Lactobacillus) and Gram-negative (Salmonella, Pseudomonas, Shigella and E.coli) bacteria strains. The essential oils have activity against all eleven microbes and the best activity determined against Streptococcus (5.3 μg/ml) were obtained. On the other hand, pseudomonas aeruginosa showed the most resistant among bacterial and fungal agent (85 μg/ml). Antimicrobial effects of B. carterii on resistance pathogens such as Pseudomonas aeroginosa and candida albicans revealed the necessity of performing expanded research about composition and property of this plant.

Keywords

El-Nagerabi, S.A.; Elshafie, A.E.; AlKhanjari, S.S.; Al-Bahry, S.N.; Elamin, M.R.; (2013). Biological activities of Boswellia sacra extracts on the growth and aflatoxins secretion of two aflatoxigenic species of Aspergillus species. Food Control; 34(2): 763-769.
Gerhardt, H.; Seifert, F.; Buvari, P.; Vogelsang, H.; Repges, R.; (2001). [Therapy of active Crohn disease with Boswellia serrata extract H 15]. Zeitschrift für Gastroenterologie; (39): 11-17.
Gupta, I.; Parihar, A.; Malhotra, P.; Gupta, S.; Lüdtke, R.; Safayhi, H.; Ammon, H. (2001). Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta medica; 67(5): 391-395.
Hasson, S.; Al-Balushi, M.; Sallam, T.; Idris, M.; Habbal, O.; Al-Jabri, A.; (2011). In vitro antibacterial activity of three medicinal plants-Boswellia (Luban) species. Asian Pacific Journal of Tropical Biomedicine; 1(2): S178-S182.
Kamatou, G.; Viljoen, A.; van Vuuren, S.; Balwanth, P.; Gosai, R.; (2009). Variation in Essential Oil Composition of Boswellia Carterii Birdw. and Its Antimicrobial Activity. African Journal of Traditional, Complementary and Alternative medicines (AJTCAM); 6: 443-444.
Lawless, J.; (1995). The Illustrated Encyclopedia of Essential Oils: The Complete Guide to the Use of Oils in Aromatherapy and Herbalism, Element Books Limited, Great Britain.
Levy, S.B.; Marshall, B.; (2004). Antibacterial resistance worldwide: causes, challenges and responses. Nature medicine; 10: S122-S129.
Mothana, R.A.; (2011). Anti-inflammatory, antinociceptive and antioxidant activities of the endemic Soqotraen Boswellia elongata Balf. f. and Jatropha unicostata Balf. f. in different experimental models. Food and Chemical Toxicology; 49(10): 2594-2599.
Schillaci, D.; Arizza, V.; Dayton, T.; Camarda, L.; Stefano, V.D.; (2008). In vitro anti‐biofilm activity of Boswellia spp. oleogum resin essential oils. Letters in applied microbiology; 47(5): 433-438.
Shao, Y.; Ho, C.-T.; Chin, C.-K.; Badmaev, V.; Ma, W.; Huang, M.-T.; (1998). Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cells in culture. Planta medica; 64(4): 328-331.
Verma, S.; Singh, S.; (2008). Current and future status of herbal medicines. Veterinary world; 1(11): 347-350.
Walmsley, S.; Devi, S.; King, S.; Schneider, R.; Richardson, S.; & Ford-Jones, L.; (1993). Invasive Aspergillus infections in a pediatric hospital: a ten-year review. The Pediatric infectious disease journal; 12(8): 673-682.