In collaboration with Payame Noor University and Iranian Society of Physiology and Pharmacology

Document Type : Article

Author

Abstract

Abstract
E.coli is known one of the most important bacteria as it causes some problems such as urinary tract and noncosomial. In this study, the antimicrobial susceptibility of E.coli in the urine culture in the west of Mazandaran province was determined. For this descriptive study, a total of 357 urine samples were collected over a 12 month period. Then all specimens included in this study were routinely cultured on the EMB and MacConkey plates. All suspected colonies were identified and confirmed by Gram staining, colony characteristics, motility and biochemical reactions by MIVP tests for each isolates. Susceptibility tests were done by disc diffusion method according NCCLS standards. Out of 357 specimens, 302 samples were positive cultures for E.coli. According to our results of antimicrobial tests, the highest susceptibilities were to Ciprofloxacin, Gentamicin, Nitrofurantoin with 48.4%, 43.3% and 37.9%, respectively. Also statistical analysis by SPSS, chi square test, showed that sensitivity to some antibiotics such as Ceftriaxon, Nalidixic acid and Ceftizoxime was significant (χ2 test, P≤5) between men and women. In our study, the highest sensitivity for E.coli isolates was to ciprofloxacin and the rate of E.coli related sensitivity for most of antibiotics was not considerable.