Hasan Baghshani; Vahide Ghodsi
Volume 6, Issue 1 , May 2017, , Pages 81-89
Abstract
Chronic cyanide intoxication has been shown to induce damage in various tissues. In the present study the effects of chronic exposure to potassium cyanide (KCN) on some oxidative stress-related parameters as well as Modulatory effects of garlic powder were studied. 18 male wistar rats were assigned into ...
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Chronic cyanide intoxication has been shown to induce damage in various tissues. In the present study the effects of chronic exposure to potassium cyanide (KCN) on some oxidative stress-related parameters as well as Modulatory effects of garlic powder were studied. 18 male wistar rats were assigned into three groups, 6 in each group. Group 1 served as control group. Group 2 received cyanide (KCN, 500 mg/L) in drinking water for 42 days. Rats in Group 3 received water containing KCN (500 mg/L in drinking) and also were fed a diet containing 5% garlic powder for 42 days. Cyanide caused increase in malondialdehyde (MDA) concentartins in all studies tissues, although the increase was only significant (P has modulatory effect on cyanide-induced oxidative stress damage in rat and could have therapeutic and prophylactic effects on cyanide poisoning.
