Biophysics
AbdolJabbar Shokri; Shahryar Saeedyan; Hamed Heidari; Aram Azizi; Zohre-Sima Gilani
Abstract
Breast cancer remains a significant global health concern, necessitating the development of innovative treatment approaches. Magnetic nanoparticles (MNPs) have emerged as a promising tool in cancer therapy due to their unique properties and controllable behavior under external magnetic fields. In this ...
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Breast cancer remains a significant global health concern, necessitating the development of innovative treatment approaches. Magnetic nanoparticles (MNPs) have emerged as a promising tool in cancer therapy due to their unique properties and controllable behavior under external magnetic fields. In this paper, a two-dimensional simulation model has been used to investigate the potential of magnetic nanoparticles for breast tumor treatment. The model considers factors such as the type and size of nanoparticles, the behavior of the particles in the presence of an applied magnetic field, and the effects of MNPs on tumor tissue. Additionally, the duration of time that nanoparticles are exposed to alternating electromagnetic fields was modeled using the finite element method and Comsol Multiphysics software package. The calculation results demonstrate that the extent of tumor and healthy tissue destruction depends on the type of nanoparticles. Furthermore, an increase in the diameter of nanoparticles leads to a decrease in the percentage of tumor tissue destruction. It is important to note that increasing the amount of heating only results in more destruction of healthy tissues, thus the most significant destruction occurred within 50 minutes.
