Abstract
Background and aims:
E.coli is known one of the most important bacteria as it causes some problems such as urinary tract and noncosomial. In this study, the antimicrobial susceptibility of E.coli in the urine culture in the west of Mazandaran province was determined.
Materials and methods:
For this descriptive study, a total of 357 urine samples were collected over a 12 month period, from September 2010 to September 2011. Then all specimens included in this study were routinely cultured on the EMB and MacConkey plates. All suspected colonies were identified and confirmed by Gram staining, colony characteristics, motility and biochemical reactions by MIVP tests for each isolates. Antibiogram tests were done by disc diffusion method according NCCLS standards.
Results:
Out of 357 specimens, 302 samples were positive cultures for E.coli. According to our results of antimicrobial tests, the highest susceptibilities were to Ciprofloxacin, Gentamicin, Nitrofurantoin with 48.4, 43.3 and 37.9 , respectively. Furthermore, lower than 10% of E.coli isolates were susceptible for antibiotics such as Ceftazidime,Tetracycline, Ampicilin, Erythromycin, Amoxicillin and Cefotaxime . Also statistical analysis by SPSS , chi square test, showed that sensitivity to some antibiotics such as Ceftriaxon, Nalidixic acid and Ceftizoxime was significant (χ2 test, P≤5) between men and women.
Conclusion: in our study, the highest sensitivity for E.coli isolates was to ciprofloxicin. In conclusion, the rate of sensitivity for most of antibiotics, which had been tested, was not considerable and it can be alarming in this part of Mazandarn.
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