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Cytotoxic effect of extract leaves of T. kotschyanus Boiss. & Hohen on Human Lang Cell

Document Type : Article

Authors

1 Associate Professor, Department of Biology, Faculty of science, Science and Research Branch, Islamic Azad University Falavarjan Branch, Isfahan, Iran

2 Ph.D. Student, Department of Biology, Islamic Azad University Damghan Branch, Semnan, Iran

Abstract

Cytotoxic effect of extract leaves of T. kotschyanus Boiss. & Hohen on Human Lang Cell. T. kotschyanus BOISS. & Hohen was used in traditional medicine such as anti-inflammation, antispasmodic and gastrointestinal aim of this study was to survey the cytotoxic effects the of ethanol of leave of thymus kotschyanus on A-549 cell line. T. kotschyanus was collected on spring 2014 from Selseleh regions of Lorestan province leaves plant for 3 days at room temperature. Dried herd powder was and extract ethanol. After preparing extract 25, 50, 100, 20, 500 μg/ml concentration for extract leveas T. kotschyanus on the cells were evaluated for 7 2 hours. Cytotoxic effects of T. kotschyanus extract leveas T. kotschyanus against cancer cell was measured by using SPSS. Results shows that, the extracts leaves ethanol T. kotschyanus has cytotoxic effects on A-549 cell lien. The finding suggest that extracts ethanol leaves T. kotschyanus to existence phenolic compounds, especially flavonoids has an inhibitory effect on the A-549 cell line.
 

Keywords

References
Ahrent, SA.; Buta, M. (2003). “mutaion and surviral in stage I non-small cell cancer: result of a prosoective study”. I Nat 1 cancer Inst.; 95(13): P. 53. 961-10.##Corner, J.; Bailey, C. (2001). “Cancer-nursing: Careincontext”. Blackwell. London. 3-46. ##Demidyuk, V.; Shubin, AV.; Kurinov, AM.; Gasno, VEV. (2013). “Alteration in Gene Expression of proprotein convertases in Human Lung cancer Have Limited Number of scenarios”. Plosone. 8(2): 5515. ##Gemal, A.; Bray, F.; Feraly, J.; Forman, D. (2011). “Global cancer statistics”. Cancer Journal for clinicians. 61(2): 69-90.##Ghasmi, M. (2003). “Thyme and savory”. Research institute of forests and rangelands. Tehran. Iran. 2003.##Horn, Papw.; Johnson, HD. (2012). “Harrison’s of Internal Medicine”. MCGraw-Hill professional. illustrated.##Kramati, K. (2005). “Effect of hydroalcohlic of thyme prostate cancer resulting from the injection of NMBA in the wistarrat”. 35(3).##Landis, S.; Bolden, T.; Wang, P. (1999). “Cancer statistics”. Ca-A- Cancer Journal for Clinicians. 49(1): 8-31.##Mehrain-Ghomi, F. (2010). “Androgen receptor requires jundas a coactivator to switch on an oxidative strees generaton pathway in prostate cancer cells”. 70: pp.4560-68.##Navaie, S. (2011). “Phytochemical study Thymus kotschyanus Boiss 8 Honen and check improve irritable bowel”. Professional doctoral thesis. Islamic Azad University Tehran.##Sakar, A.; Dshmukh, V. (2011). “Ethno Pharmacological review of traditional medicinal plants for anti-cancer activity”. 3(4): pp.298-430.##Sharma, G.; Tyagi, N.; Hooda, V. (2012). “Phytochemical and parmacological profile of lagenaria siceraria”. International Research Journal of Pharmacy, 3: pp.1-4.##Velgestein, B.; Kenneth, W. (2002). “The genetic basic of human cancer”. Mc Graw hill professional. Illustrate. 2(4): pp.203-208.##
Experimental animal Biology
Volume 4, Issue 2 - Serial Number 2
December 2015
Pages 1-6
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