In collaboration with Payame Noor University and Iranian Society of Physiology and Pharmacology

Document Type : Article

Authors

Abstract

Two hundred forty 1-d-old Ross 308 male broiler chicks were randomly allocated into 3 groups with 4 replicates. From d 14, the diets were supplemented with CoQ10 at levels of 0, 20, and 40 mg/kg, respectively. From d 14 to 42, all the chicks were exposed to low ambient temperature (10 to 15°C) to induce Ascites. Mortality was inspected to determine cause of death and diagnosis of PHS. For evaluation of antioxidant status, the parameters that were determined in plasma and liver. (GPX, SOD, TAS and MDA). Sampling of blood and liver tissue were determined at d 21 and 42. At end of the experiment (wk 6), 2 chicks from each replicate were randomly selected and slaughtered. The heart was removed; the right ventricle was dissected away from the left ventricle and septum then RV/TV calculated. The results showed that mortality due to Ascites was reduced by CoQ10 supplementation (P10 compared with the control, but no significant changes were observed on SOD activity and TAS. RV/TV was significantly decreased by 40 mg/kg CoQ10 supplementation (PP>0.05).

Keywords

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