In collaboration with Payame Noor University and Iranian Society of Physiology and Pharmacology

Abstract

Background: Based on the limited and inconsistent results about the effects of exercise on inflammatory markers in serum and saliva, this study was conducted to comparing of serum and saliva C-reactive protein (CRP) and interleukin-6 responses in healthy men following one bout exhaustive aerobic exercise.
Methods: In a quasi-experimental pre/post design, twenty two volunteer healthy men (aged 20-30 years and body fat 10-16%) participated in an exhaustive aerobic exercise (Bruce treadmill test). Serum and saliva samples were collected immediately before and after the exercise test. C-reactive protein was determined by immunophotometry and IL-6 was determined by ELISA method. Data were expressed as mean (±SD) and analyzed by t-test and Spearman's correlation coefficient at α≤0.05.
Results: The results show that the serum and saliva CRP and IL-6 were significantly increased (P

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