Payame Noor University Experimental animal Biology 2322-2387 7 4 2019 04 21 Histopathological examination of egg internal membrane on the healing of the tibia bone in the animal model of the dog Histopathological examination of egg internal membrane on the healing of the tibia bone in the animal model of the dog 99 106 5685 10.30473/eab.2019.5685 FA Elham Moghtadaee Assistant Professor, Department of Pathobiology, Faculty of Veterinary Medicine, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran Vahid Molianian Ph. D., Faculty of Veterinary Medicine, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran Journal Article 2019 05 04 <strong>Abstract </strong> <br />Nowadays the damages of the human musculoskeletal system and its healing process are crucially important. The material with the capability of prevention from infection in open fractures, reduction of treatment duration, and repair of bone tissue is economical, and it would be prioritized in usage. The egg internal membrane as a completely natural compound causes an increase in calcium absorption and accelerates the bone tissue repair process. The current study was conducted on the tibia bone of eight dogs. A cut of 10 cm length was developed in the tibia bone. 8 mm diameter cavities were developed in the mid area of the tibia bone by removing the vessels and nerves and cutting in Periosteum using the drill. The respective biomaterial was removed out of the sterile environment by Mouse-tooth forceps, and it was inserted into the bone. The tissue sections were evaluated in terms of histopathology at 0, 30, and 60 days after surgery. The results of osteoplastic changes also indicated that both control and treatment groups had an ascending bone formation process from day 0 to 60, which it was higher in all days in the treatment group compared to the control group. The bone formation level was increasing in the treatment group compared to the control group. The results obtained from Chondroplasic changes also indicated that in both groups there was a decreasing trend in Achondroplasia. <strong>Abstract </strong> <br />Nowadays the damages of the human musculoskeletal system and its healing process are crucially important. The material with the capability of prevention from infection in open fractures, reduction of treatment duration, and repair of bone tissue is economical, and it would be prioritized in usage. The egg internal membrane as a completely natural compound causes an increase in calcium absorption and accelerates the bone tissue repair process. The current study was conducted on the tibia bone of eight dogs. A cut of 10 cm length was developed in the tibia bone. 8 mm diameter cavities were developed in the mid area of the tibia bone by removing the vessels and nerves and cutting in Periosteum using the drill. The respective biomaterial was removed out of the sterile environment by Mouse-tooth forceps, and it was inserted into the bone. The tissue sections were evaluated in terms of histopathology at 0, 30, and 60 days after surgery. The results of osteoplastic changes also indicated that both control and treatment groups had an ascending bone formation process from day 0 to 60, which it was higher in all days in the treatment group compared to the control group. The bone formation level was increasing in the treatment group compared to the control group. The results obtained from Chondroplasic changes also indicated that in both groups there was a decreasing trend in Achondroplasia. https://eab.journals.pnu.ac.ir/article_5685_e5558165cb66875f0b1634bc59c28418.pdf