Veterinary
Sheida Sadat Zonoori; Mohammad Fazilati; Hossein Salavati
Abstract
Today, Spirulina micro-algae is cultivated in many countries as a rich source of protein, unsaturated fatty acids, vitamins, minerals and antioxidants. In this study, the effect of replacing spirulina microalgae powder with different amounts of industrial vitamin-mineral premix was compared as an additive ...
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Today, Spirulina micro-algae is cultivated in many countries as a rich source of protein, unsaturated fatty acids, vitamins, minerals and antioxidants. In this study, the effect of replacing spirulina microalgae powder with different amounts of industrial vitamin-mineral premix was compared as an additive to stimulate the growth performance of broiler chickens. 200 one-day-old broiler chickens were randomly selected among 3000 chickens and divided into five treatments at Mehrgan Jihad Agricultural Research Center in Kermanshah province The diet of the first group, which was considered as a control treatment, includes (100% industrial supplement and no spirulina), the first treatment T1(25% spirulina and 75% industrial supplement), the second treatment T2 (50% spirulina and 50% industrial supplement), The third treatment T3 (75% spirulina and 25% industrial supplement) and the fourth treatment T4 (100% spirulina) were used. After 42 days, there was no mortality in the treatments, in the T1, T2 and T4 treatments, live weight significantly (P<0.05) increased compared to the control group, and the amount of feed conversion ratio (FCR) in the T2 treatment decreased significantly. Therefore, T2 showed the best performance Then the biochemical parameters of blood serum in T2 were checked, which showed a significant (P<0.05) increase in glucose, total protein and albumin, HDL and LDL and a decrease in triglyceride and cholestrol levels. Based on findings, it is concluded that by replacing 50% of the industrial vitamin-mineral supplement with spirulina powder, the growth performance, feed conversion ratio and blood parameters in broilers can be improved.
Gholamreza Mahdieh najafabady; Mohammad Fazilati; Aliasghar Pilehvarian; Habib olah Nazem
Abstract
Abstract High blood pressure doubles the risk of cardiovascular disease. In addition to chemical drugs, biodegradable peptides have antihypertensive properties and the Ile-Gln-Pro peptide is one of these peptides. Spirulina is a green-blue algae of the cyanobacteria branch, which is now used as a supplement ...
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Abstract High blood pressure doubles the risk of cardiovascular disease. In addition to chemical drugs, biodegradable peptides have antihypertensive properties and the Ile-Gln-Pro peptide is one of these peptides. Spirulina is a green-blue algae of the cyanobacteria branch, which is now used as a supplement to the pharmaceutical industry. The Ile-Gln-Pro peptide was extracted from Spirulina platensis algae using an alkalase enzyme and was analyzed by filtration gel chromatography and RP-HPLC and its inhibitory effect on the ACE enzyme was investigated. ACE enzyme was inhibited by Ile-Gln-Pro peptide by non-competitive inhibition method with Ki = 5.8 μM and IC50 = 0.65 μM . According to the available information from the ACE inhibitor peptide in the BIOPEP database, a comparative study was performed on the location of amino acids in the ACE inhibitor peptide and its effect on the potency of tri-peptide inhibition. Based on SPSS software, on the 196 ACE inhibitor peptide, the presence of Lys, Gly, Thr and Pro amino acids at the end of C and His, Ala, and Met amino acids at the end of N, as well as Phe, Ala, His And His in the middle of peptide have relationship with EC50 and peptide-inhibiting potency.
