Biochemistry
Shahriar Saeidian; Nabi Khalili Aghdam; Zahra Baghaei far; Seyedeh Saleheh Hashemi
Abstract
Bromelain is an aqueous extract of pineapple contains a mixture of thiol proteases and non-protease components. In this research, the method of implementing the research was applied and quantitative, and by conducting the MTT test, information was collected. The results showed by increasing the dose ...
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Bromelain is an aqueous extract of pineapple contains a mixture of thiol proteases and non-protease components. In this research, the method of implementing the research was applied and quantitative, and by conducting the MTT test, information was collected. The results showed by increasing the dose of carbon nanotubes from 1 mg/L to 5 mg/L, the absorption efficiency increases significantly and the absorption capacity decreases and by increasing the initial concentration of Anahil drug from 50 mg/L to 300 mg/L in the dose of carbon nanotubes. No g 1/L the absorption capacity increased from 41.6 mg/g to 162.2 mg/g and in contrast the absorption efficiency decreased from 83.2 percent to 54.067 percent. The parameters of the adsorption equilibrium isotherms showed that the adsorption behavior of Anahil on carbon nanotubes follows the Freundlich model more than the Langmuir model. Also, the values obtained for parameter n in the Freundlich model for both temperatures were higher than 2, indicating the favorable adsorption of Anahil on carbon nanotubes. The results obtained from the MTT test showed that the drug Anahil in high concentrations (100 micrograms per liter) has a very strong lethal effect. It was also shown that the lethal effect of Anahil drug was more at the beginning and decreases with the passage of time. But in the case of the new drug synthesized using the introduction of the Anahil drug to the surface of carbon nanotubes, the lethality rate becomes a constant value, which indicates the gradual release of the drug over time, which is desirable for effective cancer treatment.
