In collaboration with Payame Noor University and Iranian Society of Physiology and Pharmacology

Authors

University of Guilan

Abstract

To evaluate the levels of cortisol, glucose and other possible indicators of goldfish ,Carassius auratus, in response to stress, in the first experiment, Bisphenol A (0.5 mg/L), Naphthalene (200 μg/L) and Butachlor (60%) (0.28 µg/L) were added to the aquariums water for two weeks. In the second experiment, intra-peritoneal injections of Bisphenol A, Naphthalene and Butachlor,with dose 50 mg/kg, 50 mg/kg, 20 μL on the body weight of fish were performed. On the fifth day and the end of the experiment (fifteenth day) as well as 48 hours after injection, blood sampling from caudal vein was taken and levels of cortisol, glucose, total protein and blood plasma were measured inorganic phosphorous. The results showed that the cortisol and glucose levels on day 5, there was a significant difference between control and Butachlor treatments (P 0.05). Comparing the results of the analysis of blood plasma in the fifth and fifteenth days of experiment, it was found that levels of cortisol and glucose in the treatment Butachlor had significantly different together within two periods (P

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