Experimental animal Biology

In collaboration with Payame Noor University and Iranian Society of Physiology and Pharmacology

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Editorial Board

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

Journal Metrics

News

Investigating the effect of nickel oxide nanoparticles on cellular ‎oxidative stress in Carassius auratus

Document Type : Article

Authors

Department of aquaculture, Babol ‎branch, Islamic Azad University, ‎Babol, Iran

10.30473/eab.2023.63451.1879

Abstract

Metal oxide nanoparticles are one of the most widely used compounds among nanoparticles that have wide applications in various fields and thus increase their release into the environment and their potential impact on various organisms, especially aquatic organisms in the aquatic ecosystem. Nanoparticles have high chemical and biological reactivity by increasing their surface to volume ratio, which leads to increased production of free radicals. The produced free radicals disrupt the oxidation and natural regeneration of the body's cells and cause oxidative damage in organisms and many diseases. The aim of this study was to investigate the oxidative effect of nickel nanoparticles in Carassius auratus that could open a new horizon in relation to the challenges in aquatic environments. The study groups include the control group and the treatment group with nickel nanoparticles. Each treatment with three replications each included 12 fish per replication. At the end of the period, liver samples were isolated and collected for oxidative damage. Total antioxidant levels, MDA, glutathione and the antioxidant enzymes catalase, glutathione S-transferase and superoxide dismutase were measured in all groups. The results showed that treatment with nickel oxide nanoparticles decreased the level of total anti oxidants and increased the level of MDA in the group treated with nickel oxide nanoparticles. These results showed strong evidence of inducted of cellular oxidative stress induced by exposure to nickel oxide nanoparticles. Also, by comparing the control treatments and the treatment of nickel oxide nanoparticles, it can be concluded that long-term exposure to nickel oxide nanoparticles can aggravate oxidative damage to fish liver tissue.

Keywords

Main Subjects

References
Aebi, H. (1984). Catalase in vitro. Methods in enzymology, 105, 121-126.
Aghamirkarimi, S., Mashinchian Moradi, A., Sharifpour, I., Jamili, S., &  Ghavam Mostafavi, P. (2018). Effect of copper nanoparticles in the Caspian Roach (Rutillus rutillus caspicus), changing antioxidant activities and liver histopathology.
Anoosha, F., Seyedalipour, B., & Hoseini, S. (2020). Toxicity of Nickel Nanoparticles and Nickel Chloride on Activity of Antioxidant Enzymes and Level of Lipid Peroxidation in Liver and Serum of Rats. ISMJ, 23(1), 14-26.
Baek, Y. W., & An, Y. J. (2011). Microbial toxicity of metal oxide nanoparticles (CuO, NiO, ZnO, and Sb2O3) to Escherichia coli, Bacillus subtilis, and Streptococcus aureus. Science of the total environment, 409(8), 1603-1608.
 
 
 
 
Bita, S., Mesbah, M., Shahryari, A., & Najafabadi, M. G. (2017). Effects of silver nanoparticles synthesized by bioreduction method on gill antioxidant defense system response of common carp, Cyprinus carpio. Iranian Journal of Health and Environment, 10(3), 339-348.
Blewett, T. A., & Wood, C. M. (2015). Salinity-dependent nickel accumulation and oxidative stress responses in the euryhaline killifish (Fundulus heteroclitus). Archives of environmental contamination and toxicology, 68(2), 382-394.
Bradley, P. P., Priebat, D. A., Christensen, R. D., & Rothstein, G. (1982). Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. Journal of Investigative Dermatology, 78(3), 206-209.
Buege, J. A., & Aust, S. D. (1978). Microsomal lipid peroxidation. In Methods in enzymology (Vol. 52, pp. 302-310). Academic press.
Choi, J. E., Kim, S., Ahn, J. H., Youn, P., Kang, J. S., Park, K. & Ryu, D. Y. (2010). Induction of oxidative stress and apoptosis by silver nanoparticles in the liver of adult zebrafish. Aquatic Toxicology, 100(2), 151-159.
Chowdhury, M. J., Bucking, C., & Wood, C. M. (2008). Pre-exposure to waterborne nickel downregulates gastrointestinal nickel uptake in rainbow trout: indirect evidence for nickel essentiality. Environmental science & technology, 42(4), 1359-1364.
Das, K. K., Das, S. N., & Dhundasi, S. A. (2008). Nickel, its adverse health effects & oxidative stress.Indian journal of medical research, 128(4), 412.
Di Giulio RT, Meyer JN. (2008)Reactive oxygen species and oxidative stress. The toxicology of fishes: 273-324.
Doreswamy, K., Shrilatha, B., & Rajeshkumar, T. (2004). Nickel‐induced oxidative stress in testis of mice: evidence of DNA damage and genotoxic effects. Journal of andrology, 25(6), 996-1003.
Fathi, M., Mansouri, B., Azadi, N., Davari, B., & Maleki, A. (2017). Effect of silver nanoparticles and mercury on stress index of laboratoryfish.
Giannopolitis, C. N., & Ries, S. K. (1977). Superoxide dismutases: I. Occurrence in higher plants. Plant physiology, 59(2), 309-314.
Govindasamy, R., & Rahuman, A. A. (2012). Histopathological studies and oxidative stress of synthesized silver nanoparticles in Mozambique tilapia (Oreochromis mossambicus). Journal of Environmental Sciences, 24(6), 1091-1098.
Habig, W. H., Pabst, M. J., & Jakoby, W. B. (1974). Glutathione S-transferases: the first enzymatic step in mercapturic acid formation. Journal of biological Chemistry, 249(22), 7130-7139.
Jezierska B, Witeska M. (2001) Summary of metal-induced disturbances in fish organism. Metal Toxicity to Fish Wydawnictvo Akademii Podlaskej, Siedlce. 243-214.
Joly-Pottuz, L., Vacher, B., Le Mogne, T., Martin, J. M., Mieno, T., He, C. N., & Zhao, N. Q. (2008). The role of nickel in Ni-containing nanotubes and onions as lubricant additives. Tribology Letters, 29(3), 213-219.
Karimzadeh, K., Zahmatkesh, A., & Sharifi, E. (2018). Effect of Subacute Toxicity Nano Zinc Oxide (ZnO NPs) on Oxidative Stress Enzymes of Roach (Rutilus rutilus caspicus).
Kazemian, M., & Bakhshi, M. (2019). Performance of different levels of ZnO nanoparticles on the amount of antioxidant enzymes in the liver of Koi fish (Cyprinus carpio). Journal of Animal Environment, 11(4), 243-248.
Kubrak, O. I., Husak, V. V., Rovenko, B. M., Poigner, H., Kriews, M., Abele, D., & Lushchak, V. I. (2013). Antioxidant system efficiently protects goldfish gills from Ni2+-induced oxidative stress. Chemosphere, 90(3), 971-976.
Kubrak, O. I., Rovenko, B. M., Husak, V. V., Storey, J. M., Storey, K. B., & Lushchak, V. I. (2012). Nickel induces hyperglycemia and glycogenolysis and affects the antioxidant system in liver and white muscle of goldfish Carassius auratus L. Ecotoxicology and environmental safety, 80, 231-237.
Lopes, P. A., Pinheiro, T., Santos, M. C., da Luz Mathias, M., Collares-Pereira, M. J., & Viegas-Crespo, A. M. (2001). Response of antioxidant enzymes in freshwater fish populations (Leuciscus alburnoides complex) to inorganic pollutants exposure. Science of the total environment, 280(1-3), 153-163.
Lushchak VI. (2011). Environmentally induced oxidative stress in aquatic animals. Aquatic Toxicology, 101(1): 13-30.
Lushchak, V. I. (2011). Environmentally induced oxidative stress in aquatic animals. Aquatic toxicology, 101(1), 13-30.
Matés, J. M., Pérez-Gómez, C., & De Castro, I. N. (1999). Antioxidant enzymes and human diseases. Clinical biochemistry, 32(8), 595-603.
Mohammadi, M., sattari, M., Babakhani, A., Johari, S., Ghafoori, H. (2018). Effects of iron oxide nanoparticles on the antioxidant defense system and lipid peroxidation of liver in common carp (Cyprinus carpio). Journal of Animal Environment, 10(4), 325-330.
Saini, S., Nair, N., & Saini, M. R. (2013). Embryotoxic and teratogenic effects of nickel in Swiss albino mice during organogenetic period. BioMed research international, 2013.
Sevcikova M, Modrá H, Slaninova A, Svobodova Z. (2011) Metals as a cause of oxidative stress in fish: A review. Veterinarni Medicina, 56(537-546(.
Sun, Y. P., Li, X. Q., Zhang, W. X., & Wang, H. P. (2007). A method for the preparation of stable dispersion of zero-valent iron nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 308(1-3), 60-66.
Wells, M. L., Smith, G. J., & Bruland, K. W. (2000). The distribution of colloidal and particulate bioactive metals in Narragansett Bay, RI. Marine Chemistry, 71(1-2), 143-163.
Experimental animal Biology
Volume 11, Issue 4 - Serial Number 44
June 2023
Pages 1-14
Files
Share
How to cite
Statistics