The Effect of Intraaccumbance Injection of Ascorbate Oxidase and Dopamine D2 agonist, Bromocriptine on Adult Male Rats Feeding
A.
Aminizade
Department of Biology, Shahid Bahonar University, Kerman
author
M.
Abbasnejad
Department of Biology, Shahid Bahonar University, Kerman
author
text
article
2012
per
Experimental animal Biology
Payame Noor University
2322-2387
1
v.
2
no.
2012
1
10
https://eab.journals.pnu.ac.ir/article_697_668b001795057446befe49ee587a69f2.pdf
Affinity Maturation of Herceptin via Rational Design of a Point Mutation:
A Molecular Dynamic Simulation Study
M.
Jamalan
Shoushtar Branch, Islamic Azad University,
Shuoshtar
author
E.
Barzegari Asad-Abadi
Shoushtar Branch, Islamic Azad University,
Shuoshtar
author
text
article
2012
per
Experimental animal Biology
Payame Noor University
2322-2387
1
v.
2
no.
2012
11
16
https://eab.journals.pnu.ac.ir/article_698_26be77679855a71a474c947198d5c3b1.pdf
Studying the Effect of Static Magnetic Field on Induced Apoptosis in Mesenchymal Bone Marrow Stem Cells of Rat
A.
Sabet
Department of Biophysics, Faculty of Bioscience, Tarbiat Modares University, Tehran,
author
P.
Abdolmaleki
Department of Biophysics, Faculty of Bioscience, Tarbiat Modares University, Tehran,
author
S. J.
Mowla
Department of Genetics, Faculty of Bioscience, Tarbiat Modares University, Tehran,
author
F.
Ghanati
Department of Plant Biology, Faculty of Bioscience, Tarbiat Modares University, Tehran
author
text
article
2012
per
Experimental animal Biology
Payame Noor University
2322-2387
1
v.
2
no.
2012
17
23
https://eab.journals.pnu.ac.ir/article_699_4dc25e52dad63d6d4193ee42218781fb.pdf
Role of the Androgen Receptors in Memory Impairment in Mature
Male Rats
S. R.
Pourrabi1
Department of Biology, Science and Research Branch, Islamic Azad University, Fars,
author
A. R.
Mohajjel Nayebi
Department of pharmacology and toxicology, Tabriz University of Medical Sciences, Tabriz
author
S. E.
Hossini
Department of Biology, Science and Research Branch, Islamic Azad University, Fars,
author
text
article
2012
per
Steroidal sex hormones especially testosterone have a protective effect in neurodegenerative events such as Alzheimer Disease. The present study was designed to explore effect of testosterone and androgen receptors in memory impairment induced by intra- cerebroventricular (icv) injection of streptozotocin (STZ) as a model of sporadic AD. In this research animals were divided randomly into 11 equal groups. Experimental model of AD was induced by bilateral icv injection of STZ. STZ-induced memory impairment was assessed two weeks after the last dose of STZ by using a passive avoidance task. The interval between the placement of animals in the illuminated chamber and the entry into the dark chamber was measured as step-through latency (STL). Castration was performed by surgical removing of testis and behavioral study of memory impairment was done after 4 weeks. Results of this study showed that icv injection of STZ could induce marked (p<0.001) memory impairment. Memory was worsened in castrated rats (P<0.001) when compared with normal and sham-operated animals. Testosterone replacement therapy in 4 week castrated rats restored memory up to the level of control groups. Testosterone had not any significant effect on memory impairments of non-castrated rats. According to the obtained results it can be concluded that testosterone improves cognitive and memory impairment of AD.
Experimental animal Biology
Payame Noor University
2322-2387
1
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2
no.
2012
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32
https://eab.journals.pnu.ac.ir/article_700_1d1f676966ad8417582bf87d0b9e792b.pdf
B Cell Line (Raji) and T Cell Line
(molt-4) Tolerance to Low Concentration Zinc Chloride in Vitro Study
S.
Nasri
Assistant Professor, Department of Bioloty, Payam-e-Noor Uiversity, Tehran,
author
sayeh.
bidaran
Animal Physiology, Department of Biology, Payam-e-Noor Uiversity, Tehran
author
P.
Nasiri
Associate Professor, Academic Department of Statistics and Mathematics, Payam-e-Noor Uiversity, Tehran
author
text
article
2012
per
Introduction & Objective: Zinc is an essential element for the immune system. This element has different effects on immune system activity. On the other hand, different serum Zn levels also alter normal B-cell line and T-cell line functions. The present study was carried out to assess B cell line and T cell line tolerance to low concentration Zinc Chloride In vitro study. This experimental study was conducted at the Payame Noor University of Tehran in 2010. The B- cell line and T-cell line were exposed to 1, 5, 10, 20, 30, 40, 50, 75, 100,125, 150,175 and 200 µm (λ) of Zinc Chloride followed by incubation at 12, 24, 36, 48, 60 and 72 hrs. Viability of B- cell line (Raji) and T-cell line (molt-4) were evaluated with hemocytometer method and percentage of living cells have been considered as cellular tolerance index to cytotoxic effects of Zinc chloride. The results were analyzed by SPSS software, version 18 using T-test and Kruskal-Wallis test. In this study, the results showed Zinc chloride concentrations up to 40 µm (λ) at different incubation time points (12-72 hrs) had no effects on B cell line and T cell line viability ( p> 0.05) With 50-200 µm (λ) concentrations, Zinc at different incubation time points (12-72 hrs) tolerance B cell and T cell line decreased and viability decreased significantly when compared with the control group and test groups up to 40 µm (λ) concentration ( p< 0.05). All groups at different after incubation time , Zinc concentrations (50-200 µm ) B cell and T cell line tolerance decreased significantly when compared with Zinc chloride concentrations up to 40 µm (λ) ( p< 0.05). Zinc is necessary for the normal function of the immune system. A variety of in vitro effects of zinc on B cell line and T cell line depend on the zinc concentration. High dosages of zinc evoke negative effects on B cell line and T cell line. An excess of zinc can inhibit B- cell line and T-cell line function.
Experimental animal Biology
Payame Noor University
2322-2387
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2
no.
2012
33
42
https://eab.journals.pnu.ac.ir/article_701_4e2ab399d67b402c00c82c70695f1cc9.pdf
Prediction of HBsAg Conformational Changes in Iranian Patients with Occult Hepatitis B Infection with Bioinformatics Tools
s.
soofian
Assistant Professor, Payame Noor University
author
text
article
2012
per
Experimental animal Biology
Payame Noor University
2322-2387
1
v.
2
no.
2012
49
55
https://eab.journals.pnu.ac.ir/article_703_5035c4c6e02bf78f67ef14786c481f6b.pdf
Study on Fauna Scorpion of Ilam Province, Western of Iran
I.
Gowhari
M. Sc. Zoology, Payam-e-Noor University
author
Sh.
Pashaei Rad
Faculty Member of Shahid Beheshti University, Tehran
author
Sh.
Navidpour
Razi Reference Laboratory of Scorpion Research, Razi Vaccine and Serum Research Institute, Karaj
author
S.
Molaei Birgani
M. Sc. Zoology, Payam-e-Noor University
author
text
article
2012
per
Experimental animal Biology
Payame Noor University
2322-2387
1
v.
2
no.
2012
43
47
https://eab.journals.pnu.ac.ir/article_702_441f9dc712205983b859de8471fe83c8.pdf
Effcts of Glutamine on Oxidative Stress, Nitrogen Metabolism and Performance of Holestin Dairy Cows in Transition Period
T.
Tanha
Assistant Professor, Payam-e-Noor University, Tehran
author
H.
Amanlo
Associate Professor, Agriculture Faculty, Zanjan
author
M.
Fathi
Assistant Professor, Payam-e-Noor University
author
text
article
2012
per
Experimental animal Biology
Payame Noor University
2322-2387
1
v.
2
no.
2012
57
65
https://eab.journals.pnu.ac.ir/article_704_947e92ef141b8312a00cd008155e143d.pdf
Distribution Pattern and Morphology of Apathya cappadocica urmiana (Reptilia: Lacertidae) in Iran
H.
Darvishnia
Department of Biology, Pyame Noor University
author
H.
Feizi
Department of Biology, Razi University, Kermanshah
author
M.
Rajabizadeh
Department of Biodiversity, International Center for Science, High Technology & Environmental Sciences, Kerman
author
text
article
2012
per
Experimental animal Biology
Payame Noor University
2322-2387
1
v.
2
no.
2012
67
72
https://eab.journals.pnu.ac.ir/article_705_c8a1740722fd6463c40994ddebe65edf.pdf